Harvard COSMOS Trial — 21,442 participants 27% reduction in cardiovascular death 500mg cocoa flavanols per serve Academy of Nutrition & Dietetics recommended Third-party tested — no heavy metals Nitric oxide mechanism — documented biochemistry Harvard COSMOS Trial — 21,442 participants 27% reduction in cardiovascular death 500mg cocoa flavanols per serve Academy of Nutrition & Dietetics recommended Third-party tested — no heavy metals Nitric oxide mechanism — documented biochemistry
Harvard-Validated · Clinically Dosed

Your blood vessels
are rusting.
This fixes that.

The 3,500-year-old compound Harvard just proved changes everything about heart and brain health.

A landmark study of 21,442 people found that those who took 500mg of cocoa flavanols daily were 27% less likely to die from cardiovascular disease. The ones who took it consistently? 39% less likely.

That study was run by Harvard. Published in the American Journal of Clinical Nutrition. And the compound they tested is what's in every scoop of Cavora.

27%reduction in cardiovascular death
21KHarvard trial participants
500mgexact clinical dose per serve
Cavora Circulation Blend

Cavora Circulation Blend

Cocoa Flavanol Powder · 30 Servings

$39.9930-day guarantee
500mg flavanols — the exact Harvard dose
Lab research
The COSMOS Trial · Harvard Medical School

The largest flavanol
trial ever conducted.

21,442 Americans. Randomised, double-blind, placebo-controlled. Led by Harvard's Brigham and Women's Hospital. Funded primarily by the National Institutes of Health. Over 3.6 years, researchers tracked every cardiovascular event — heart attacks, strokes, deaths.

People who consistently took 500mg of cocoa flavanols daily were dramatically less likely to die from a cardiovascular event. Not hospitalised. Not treated. Die.

Published · American Journal of Clinical Nutrition · 2022
39%Reduction in CVD deathamong consistent users (per-protocol)
27%Overall CVD death reductionintention-to-treat analysis
16%Reduction in major eventsstatistically significant
21,442Trial participantsone of the largest ever
The Mechanism

Not a theory.
Documented biochemistry.

01

Your vessels lose flexibility with age

From your 40s onward, the inner lining of your blood vessels becomes stiffer and less responsive. Blood pressure creeps up, blood flow to the brain decreases, and your heart works harder than it should.

02

Flavanols trigger nitric oxide production

Cocoa flavanols signal the endothelium to produce nitric oxide — your body's natural vasodilator. Researchers proved this by blocking nitric oxide synthesis with a drug and watching the entire flavanol effect disappear.

03

Blood flow restores — to heart and brain

Columbia University researchers watched this happen live on fMRI — flavanols increased blood volume in the hippocampus directly proportional to improved memory scores.

Nitric oxide mechanism — healthy blood flow

"Participants given a high-flavanol cocoa drink showed a 29% increase in arterial dilation within 12 hours. When nitric oxide synthesis was blocked, the effect completely disappeared."

Documented in Nature, PNAS & Circulation

Columbia University used fMRI to measure actual increases in blood volume in the dentate gyrus — the hippocampal region responsible for forming new memories — after 3 months of supplementation.

The Academy of Nutrition and Dietetics issued its first-ever dietary recommendation for a specific bioactive compound in October 2022. That compound was flavanols. At 400–600mg per day.

Cavora premium cacao concentrate

Premium cacao.
Clinically dosed.

500mg of standardised cocoa flavanols per serve. The exact dose used in Harvard's landmark 21,442-person COSMOS trial.

The Inconvenient Truth

Dark chocolate
isn't enough.

Dark chocolate vs raw cacao comparison
500mg from milk chocolate = 50 servingsEvery single day
8,000 cal
500mg from dark chocolate = 100–200gOf the highest quality available
~900 cal
Dutch processing destroys up toof flavanols in commercial cocoa
90%
One scoop of CavoraExact clinical dose — no calories, no sugar
500mg

The '% cacao' on the label means nothing

No legal requirement exists to disclose flavanol content. The percentage measures total cacao-derived ingredients — including cocoa butter, which contains zero flavanols.

Dutch processing wipes out the benefit

Invented in 1828, alkalization destroys 60–90% of flavanols. Most commercial dark chocolate uses this process. If your label says "processed with alkali," the flavanols are largely gone.

Cavora delivers the dose the research actually used

500mg of standardised cocoa flavanols per serve. Consistent, measured, third-party tested. No Dutch processing. No guesswork.

Raw cacao beans macro

3,500 years of
ancient wisdom.

Long before Harvard studied it, the Kuna people of Panama knew something extraordinary about cacao. Here's the discovery that changed everything.

Panama island aerial view
The Discovery That Started Everything

A tribe with no heart disease.
Harvard spent a decade finding out why.

In the 1940s, a US military cardiologist noticed the Kuna people of Panama had almost no hypertension and dramatically longer lives. Harvard's Norman Hollenberg thought it was genetic — until he tested Kuna who had moved to Panama City and found their disease rates had become identical to their neighbours.

3–5cups of flavanol-rich cacao drunk daily by island Kuna
1,280%higher cardiovascular death rate for Kuna who moved to the city
Samegenetics — protection vanished when the cacao stopped
"The Kuna who moved to the city had blood pressure and cardiovascular disease rates virtually identical to their non-Kuna neighbours. The genetic protection had simply... vanished."

Hollenberg et al., Brigham and Women's Hospital / Harvard Medical School, published in Hypertension

Family playing board game together

Still sharp.
Still present.

The goal isn't just a longer life. It's being mentally here for the moments that matter. That's what the science is really about.

Verified Reviews

What consistent use
looks like.

4.8
from 200+ reviews

"I'm a 59-year-old software developer who always feared I'd slow down mentally. But I can effortlessly keep up with all the twenty-something computer geeks fresh out of college. I can easily remember things that other people seem to forget."

ST
Stephen T.
March 2026
Verified Purchase

"Just a few weeks in and my blood pressure is down to unbelievable levels. I am floored by the results. I will take this over blood pressure medication any day — the side effects from BP meds were destroying my quality of life."

JM
James M.
March 2026
Verified Purchase

"As a pharmacist, I'm always sceptical about non-medicinal claims. But my cholesterol was finally in an acceptable range — lower than it's been in 15+ years. I can't deny that this has made a measurable difference."

LK
Linda K. — Pharmacist
February 2026
Verified Purchase
30Day
Guarantee

Try it. Feel the difference. Or we'll refund you.

Add Cavora to your daily routine for 30 days. If you don't notice a difference — in energy, focus, or how you feel — contact us for a full refund. No hoops. No excuses.

Common Questions

Honest answers,
no marketing fluff.

I already eat dark chocolate. Isn't that enough?

Almost certainly not. Most commercial dark chocolate uses Dutch-processed cocoa, destroying 60–90% of flavanols. To reliably hit 500mg, you'd need 100–200g of high-quality dark chocolate daily — roughly 500–1,000 calories of sugar and saturated fat. Every day.

The COSMOS trial was funded by Mars. Should I trust it?

The trial was led by Harvard's Brigham and Women's Hospital and funded primarily by the National Institutes of Health. The research team is independent of Mars. The results have been replicated across multiple independent trials.

I'm on blood pressure medication. Can I take this?

Always discuss supplements with your doctor, especially on prescription medication. Many people use flavanol supplements alongside existing protocols. Your GP can advise on what's right for you.

How long before I notice results?

Short-term studies show measurable improvements in arterial dilation within hours. Blood pressure and cognitive improvements observed within 2–8 weeks. The cardiovascular death reduction in COSMOS built over 3.6 years — some benefits compound over time.

Is there heavy metal contamination risk?

A real concern across the cocoa industry. Cavora is third-party tested with rigorous quality controls to minimise contamination. Documentation available on request.

Ready to give your heart and brain what the science says they need?

500mg of cocoa flavanols per serve. The exact dose used in the Harvard trial. Third-party tested. 30-day satisfaction guarantee.

500mg flavanols — Harvard clinical dose
No Dutch processing — flavanols preserved
Third-party tested for heavy metals
Free shipping across Australia
30-day money-back guarantee
Shop Cavora — $39.99 AUD
† These statements have not been evaluated by the TGA or FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your physician before beginning any supplement regimen.